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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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Id | http://purl.bioontology.org/ontology/NDFRT/N0000169389
http://purl.bioontology.org/ontology/NDFRT/N0000169389
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Preferred Name | Immunoglobulin Fab Fragments [Chemical/Ingredient] |
Synonyms |
Immunoglobulin Fab Fragments
Immunoglobulins, Fab
Immunoglobulin Fab Fragment
Immunoglobulins, Fab Fragment
Fab Fragments
Fab Immunoglobulin Fragments
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Type | http://www.w3.org/2002/07/owl#Class |
All Properties
altLabel |
Immunoglobulin Fab Fragments
Immunoglobulins, Fab
Immunoglobulin Fab Fragment
Immunoglobulins, Fab Fragment
Fab Fragments
Fab Immunoglobulin Fragments
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prefLabel |
Immunoglobulin Fab Fragments [Chemical/Ingredient]
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notation |
N0000169389
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MESH DEFINITION |
Univalent antigen-binding fragments composed of one entire IMMUNOGLOBULIN LIGHT CHAIN and the amino terminal end of one of the IMMUNOGLOBULIN HEAVY CHAINS from the hinge region, linked to each other by disulfide bonds. Fab contains the IMMUNOGLOBULIN VARIABLE REGIONS, which are part of the antigen-binding site, and the first IMMUNOGLOBULIN CONSTANT REGIONS. This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.
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MESH UI |
M0011126
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subClassOf | |
Semantic type UMLS property | |
MeSH name |
Immunoglobulin Fab Fragments
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NDFRT kind |
INGREDIENT_KIND
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type | |
tui |
T116
T129
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NUI |
N0000169389
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cui |
C0021031
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MESH DUI |
D007140
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