Preferred Name

Immunoglobulin Fc Fragments [Chemical/Ingredient]
Synonyms

Fc Immunoglobulins

Immunoglobulins, Fc Fragment

Immunoglobulin Fc Fragments

Fc Fragments

Immunoglobulin Fc Fragment

Immunoglobulins, Fc

ID

http://purl.bioontology.org/ontology/NDFRT/N0000169388

altLabel

Fc Immunoglobulins

Immunoglobulins, Fc Fragment

Immunoglobulin Fc Fragments

Fc Fragments

Immunoglobulin Fc Fragment

Immunoglobulins, Fc

cui

C0021032

MESH DEFINITION

Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN.

MESH DUI

D007141

MeSH name

Immunoglobulin Fc Fragments

MESH UI

M0011127

NDFRT kind

INGREDIENT_KIND

notation

N0000169388

NUI

N0000169388

prefLabel

Immunoglobulin Fc Fragments [Chemical/Ingredient]

tui

T116

T129

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000169387

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