loading...| Preferred Name |
Immunoglobulin Fc Fragments [Chemical/Ingredient] |
|
| Synonyms |
Fc Immunoglobulins |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000169388 |
|
| altLabel |
Fc Immunoglobulins Immunoglobulins, Fc Fragment Immunoglobulin Fc Fragments Fc Fragments Immunoglobulin Fc Fragment Immunoglobulins, Fc |
|
| cui |
C0021032 |
|
| MESH DEFINITION |
Crystallizable fragments composed of the carboxy-terminal halves of both IMMUNOGLOBULIN HEAVY CHAINS linked to each other by disulfide bonds. Fc fragments contain the carboxy-terminal parts of the heavy chain constant regions that are responsible for the effector functions of an immunoglobulin (COMPLEMENT fixation, binding to the cell membrane via FC RECEPTORS, and placental transport). This fragment can be obtained by digestion of immunoglobulins with the proteolytic enzyme PAPAIN. |
|
| MESH DUI |
D007141 |
|
| MeSH name |
Immunoglobulin Fc Fragments |
|
| MESH UI |
M0011127 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000169388 |
|
| NUI |
N0000169388 |
|
| prefLabel |
Immunoglobulin Fc Fragments [Chemical/Ingredient] |
|
| tui |
T116 T129 |
|
| subClassOf |