Preferred Name | Complement Factor I [Chemical/Ingredient] | |
Synonyms |
C3b Inactivator C4bC3bINA C3b-C4b Inactivator C4b-C3b-INA Complement 3b-Complement 4b Inactivator Complement Factor I Complement C4b-C3b Inactivator |
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ID |
http://purl.bioontology.org/ontology/NDFRT/N0000169307 |
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altLabel |
C3b Inactivator C4bC3bINA C3b-C4b Inactivator C4b-C3b-INA Complement 3b-Complement 4b Inactivator Complement Factor I Complement C4b-C3b Inactivator |
|
cui |
C0110533 |
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MESH DEFINITION |
A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator. |
|
MESH DUI |
D017244 |
|
MeSH name |
Complement Factor I |
|
MESH UI |
M0026165 |
|
NDFRT kind |
INGREDIENT_KIND |
|
notation |
N0000169307 |
|
NUI |
N0000169307 |
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prefLabel |
Complement Factor I [Chemical/Ingredient] |
|
tui |
T116 T129 T126 |
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subClassOf |