Preferred Name

Complement Factor I [Chemical/Ingredient]
Synonyms

C3b Inactivator

C4bC3bINA

C3b-C4b Inactivator

C4b-C3b-INA

Complement 3b-Complement 4b Inactivator

Complement Factor I

Complement C4b-C3b Inactivator

ID

http://purl.bioontology.org/ontology/NDFRT/N0000169307

altLabel

C3b Inactivator

C4bC3bINA

C3b-C4b Inactivator

C4b-C3b-INA

Complement 3b-Complement 4b Inactivator

Complement Factor I

Complement C4b-C3b Inactivator

cui

C0110533

MESH DEFINITION

A plasma serine proteinase that cleaves the alpha-chains of C3b and C4b in the presence of the cofactors COMPLEMENT FACTOR H and C4-binding protein, respectively. It is a 66-kDa glycoprotein that converts C3b to inactivated C3b (iC3b) followed by the release of two fragments, C3c (150-kDa) and C3dg (41-kDa). It was formerly called KAF, C3bINF, or enzyme 3b inactivator.

MESH DUI

D017244

MeSH name

Complement Factor I

MESH UI

M0026165

NDFRT kind

INGREDIENT_KIND

notation

N0000169307

NUI

N0000169307

prefLabel

Complement Factor I [Chemical/Ingredient]

tui

T116

T129

T126

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000169306

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