loading...| Preferred Name | Complement Membrane Attack Complex [Chemical/Ingredient] | |
| Synonyms |
C5b-9 C5b-8-poly-C9 Cytolytic Terminal Complement Complex C 5b-9 Membrane Attack Complex Complement Complex C5b-9 Terminal Complement Complex Complement Membrane Attack Complex |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000169303 |
|
| altLabel |
C5b-9 C5b-8-poly-C9 Cytolytic Terminal Complement Complex C 5b-9 Membrane Attack Complex Complement Complex C5b-9 Terminal Complement Complex Complement Membrane Attack Complex |
|
| cui |
C0009545 |
|
| MESH DEFINITION |
A product of COMPLEMENT ACTIVATION cascade, regardless of the pathways, that forms transmembrane channels causing disruption of the target CELL MEMBRANE and cell lysis. It is formed by the sequential assembly of terminal complement components (COMPLEMENT C5B; COMPLEMENT C6; COMPLEMENT C7; COMPLEMENT C8; and COMPLEMENT C9) into the target membrane. The resultant C5b-8-poly-C9 is the "membrane attack complex" or MAC. |
|
| MESH DUI |
D015938 |
|
| MeSH name |
Complement Membrane Attack Complex |
|
| MESH UI |
M0024383 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000169303 |
|
| NUI |
N0000169303 |
|
| prefLabel |
Complement Membrane Attack Complex [Chemical/Ingredient] |
|
| tui |
T116 T129 |
|
| subClassOf |