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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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Preferred Name | Complement C9 [Chemical/Ingredient] | |
Synonyms |
C9 Complement Complement 9 Complement Component 9 Complement C9 |
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ID |
http://purl.bioontology.org/ontology/NDFRT/N0000169270 |
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altLabel |
C9 Complement Complement 9 Complement Component 9 Complement C9
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cui |
C0009526
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MESH DEFINITION |
A 63-kDa serum glycoprotein encoded by gene C9. Monomeric C9 (mC9) binds the C5b-8 complex to form C5b-9 which catalyzes the polymerization of C9 forming C5b-p9 (MEMBRANE ATTACK COMPLEX) and transmembrane channels leading to lysis of the target cell. Patients with C9 deficiency suffer from recurrent bacterial infections.
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MESH DUI |
D003186
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MeSH name |
Complement C9
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MESH UI |
M0004941
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NDFRT kind |
INGREDIENT_KIND
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notation |
N0000169270
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NUI |
N0000169270
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prefLabel |
Complement C9 [Chemical/Ingredient]
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tui |
T116 T129
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subClassOf |
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