loading...| Preferred Name |
Receptor, Epidermal Growth Factor [Chemical/Ingredient] |
|
| Synonyms |
TGF-alpha Receptor |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000168855 |
|
| altLabel |
TGF-alpha Receptor Receptor, TGF-alpha Resceptor Tyrosine-protein Kinase erbB-1 Receptor, Epidermal Growth Factor Urogastrone Receptor EGF Receptor Epidermal Growth Factor Receptor Kinase Receptor, Transforming-Growth Factor alpha Epidermal Growth Factor Receptor Protein-Tyrosine Kinase Receptor, Urogastrone Receptor, ErbB-1 Receptor, EGF Transforming Growth Factor alpha Receptor Epidermal Growth Factor Receptor erbB-1 Proto-Oncogene Protein c-erbB-1 Protein Proto-oncogene c-ErbB-1 Protein |
|
| cui |
C0034802 |
|
| MESH DEFINITION |
A cell surface receptor involved in regulation of cell growth and differentiation. It is specific for EPIDERMAL GROWTH FACTOR and EGF-related peptides including TRANSFORMING GROWTH FACTOR ALPHA; AMPHIREGULIN; and HEPARIN-BINDING EGF-LIKE GROWTH FACTOR. The binding of ligand to the receptor causes activation of its intrinsic tyrosine kinase activity and rapid internalization of the receptor-ligand complex into the cell. |
|
| MESH DUI |
D011958 |
|
| MeSH name |
Receptor, Epidermal Growth Factor |
|
| MESH UI |
M0018582 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000168855 |
|
| NUI |
N0000168855 |
|
| prefLabel |
Receptor, Epidermal Growth Factor [Chemical/Ingredient] |
|
| tui |
T116 T126 T192 |
|
| subClassOf |