loading...| Preferred Name | Receptors, N-Methyl-D-Aspartate [Chemical/Ingredient] | |
| Synonyms |
Receptors, N-Methyl-D-Aspartate NMDA Receptors Receptors, NMDA Receptors, N-Methylaspartate N-Methylaspartate Receptors N-Methyl-D-Aspartate Receptors NMDA Receptor-Ionophore Complex |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000168777 |
|
| altLabel |
Receptors, N-Methyl-D-Aspartate NMDA Receptors Receptors, NMDA Receptors, N-Methylaspartate N-Methylaspartate Receptors N-Methyl-D-Aspartate Receptors NMDA Receptor-Ionophore Complex |
|
| cui |
C0080093 |
|
| MESH DEFINITION |
A class of ionotropic glutamate receptors characterized by affinity for N-methyl-D-aspartate. NMDA receptors have an allosteric binding site for glycine which must be occupied for the channel to open efficiently and a site within the channel itself to which magnesium ions bind in a voltage-dependent manner. The positive voltage dependence of channel conductance and the high permeability of the conducting channel to calcium ions (as well as to monovalent cations) are important in excitotoxicity and neuronal plasticity. |
|
| MESH DUI |
D016194 |
|
| MeSH name |
Receptors, N-Methyl-D-Aspartate |
|
| MESH UI |
M0024713 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000168777 |
|
| NUI |
N0000168777 |
|
| prefLabel |
Receptors, N-Methyl-D-Aspartate [Chemical/Ingredient] |
|
| tui |
T116 T192 |
|
| subClassOf |