loading...| Preferred Name | Integrin alpha Chains [Chemical/Ingredient] | |
| Synonyms |
alpha Integrins Integrin alpha Chains Integrin alpha Subunits |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000168743 |
|
| altLabel |
alpha Integrins Integrin alpha Chains Integrin alpha Subunits |
|
| cui |
C1136252 |
|
| MESH DEFINITION |
The alpha subunits of integrin heterodimers (INTEGRINS), which mediate ligand specificity. There are approximately 18 different alpha chains, exhibiting great sequence diversity; several chains are also spliced into alternative isoforms. They possess a long extracellular portion (1200 amino acids) containing a MIDAS (metal ion-dependent adhesion site) motif, and seven 60-amino acid tandem repeats, the last 4 of which form EF HAND MOTIFS. The intracellular portion is short with the exception of INTEGRIN ALPHA4. |
|
| MESH DUI |
D039001 |
|
| MeSH name |
Integrin alpha Chains |
|
| MESH UI |
M0417909 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000168743 |
|
| NUI |
N0000168743 |
|
| prefLabel |
Integrin alpha Chains [Chemical/Ingredient] |
|
| tui |
T116 T123 |
|
| subClassOf |
| Delete | Mapping To | Ontology | Source |
|---|---|---|---|
| http://purl.bioontology.org/ontology/MSHFRE/D039001 | MSHFRE | CUI | |
| http://purl.bioontology.org/ontology/MESH/D039001 | MESH | CUI |