Preferred Name

Farnesyl-Diphosphate Farnesyltransferase [Chemical/Ingredient]
Synonyms

Farnesyldiphosphate-Farnesyldiphosphate Farnesyltransferase

Presqualene-Diphosphate Synthase

Squalene Synthase

Squalene Synthetase

Farnesyl-Diphosphate Farnesyltransferase

FPP-FPP Farnesyl Transferase

ID

http://purl.bioontology.org/ontology/NDFRT/N0000168314

altLabel

Farnesyldiphosphate-Farnesyldiphosphate Farnesyltransferase

Presqualene-Diphosphate Synthase

Squalene Synthase

Squalene Synthetase

Farnesyl-Diphosphate Farnesyltransferase

FPP-FPP Farnesyl Transferase

cui

C0597790

MESH DEFINITION

The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway.

MESH DUI

D013186

MeSH name

Farnesyl-Diphosphate Farnesyltransferase

MESH UI

M0020401

NDFRT kind

INGREDIENT_KIND

notation

N0000168314

NUI

N0000168314

prefLabel

Farnesyl-Diphosphate Farnesyltransferase [Chemical/Ingredient]

tui

T116

T126

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000168308

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