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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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| Preferred Name | Farnesyl-Diphosphate Farnesyltransferase [Chemical/Ingredient] | |
| Synonyms |
Farnesyldiphosphate-Farnesyldiphosphate Farnesyltransferase Presqualene-Diphosphate Synthase Squalene Synthase Squalene Synthetase Farnesyl-Diphosphate Farnesyltransferase FPP-FPP Farnesyl Transferase |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000168314 |
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| altLabel |
Farnesyldiphosphate-Farnesyldiphosphate Farnesyltransferase Presqualene-Diphosphate Synthase Squalene Synthase Squalene Synthetase Farnesyl-Diphosphate Farnesyltransferase FPP-FPP Farnesyl Transferase
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| cui |
C0597790
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| MESH DEFINITION |
The first committed enzyme of the biosynthesis pathway that leads to the production of STEROLS. it catalyzes the synthesis of SQUALENE from farnesyl pyrophosphate via the intermediate PRESQUALENE PYROPHOSPHATE. This enzyme is also a critical branch point enzyme in the biosynthesis of ISOPRENOIDS that is thought to regulate the flux of isoprene intermediates through the sterol pathway.
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| MESH DUI |
D013186
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| MeSH name |
Farnesyl-Diphosphate Farnesyltransferase
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| MESH UI |
M0020401
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| NDFRT kind |
INGREDIENT_KIND
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| notation |
N0000168314
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| NUI |
N0000168314
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| prefLabel |
Farnesyl-Diphosphate Farnesyltransferase [Chemical/Ingredient]
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| tui |
T116 T126
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| subClassOf |
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