loading...| Preferred Name | Calcineurin [Chemical/Ingredient] | |
| Synonyms |
Calcineurin Protein Phosphatase-2B Protein Phosphatase 3 |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000167646 |
|
| altLabel |
Calcineurin Protein Phosphatase-2B Protein Phosphatase 3 |
|
| cui |
C0054450 |
|
| MESH DEFINITION |
A CALCIUM and CALMODULIN-dependent serine/threonine protein phosphatase that is composed of the calcineurin A catalytic subunit and the calcineurin B regulatory subunit. Calcineurin has been shown to dephosphorylate a number of phosphoproteins including HISTONES; MYOSIN LIGHT CHAIN; and the regulatory subunits of CAMP-DEPENDENT PROTEIN KINASES. It is involved in the regulation of signal transduction and is the target of an important class of immunophilin-immunosuppressive drug complexes. |
|
| MESH DUI |
D019703 |
|
| MeSH name |
Calcineurin |
|
| MESH UI |
M0029257 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000167646 |
|
| NUI |
N0000167646 |
|
| prefLabel |
Calcineurin [Chemical/Ingredient] |
|
| tui |
T116 T126 |
|
| subClassOf |