loading...| Preferred Name |
1-Alkyl-2-acetylglycerophosphocholine Esterase [Chemical/Ingredient] |
|
| Synonyms |
Platelet-Activating Factor Hydrolase |
|
| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000167633 |
|
| altLabel |
Platelet-Activating Factor Hydrolase PAF 2-Acylhydrolase Lp-PLA2 1-Alkyl-2-acetylglycerophosphocholine Esterase Lipoprotein-Associated Phospholipase A(2) PAF Acetylhydrolase PAF Acetylhydrolase II PAF 2-Acetylhydrolase Lipoprotein-Associated Phospholipase A2 Lp-PLA(2) |
|
| cui |
C0914069 |
|
| MESH DEFINITION |
A lipoprotein-associated PHOSPHOLIPASE A2 which modulates the action of PLATELET ACTIVATING FACTOR by hydrolyzing the SN-2 ester bond to yield the biologically inactive lyso-platelet-activating factor. It has specificity for phospholipid substrates with short-chain residues at the SN-2 position, but inactive against long-chain phospholipids. Deficiency in this enzyme is associated with many diseases including ASTHMA, and HYPERCHOLESTEROLEMIA. |
|
| MESH DUI |
D043203 |
|
| MeSH name |
1-Alkyl-2-acetylglycerophosphocholine Esterase |
|
| MESH UI |
M0118406 |
|
| NDFRT kind |
INGREDIENT_KIND |
|
| notation |
N0000167633 |
|
| NUI |
N0000167633 |
|
| prefLabel |
1-Alkyl-2-acetylglycerophosphocholine Esterase [Chemical/Ingredient] |
|
| tui |
T116 T126 |
|
| subClassOf |