National Drug File - Reference Terminology - Pyrrolizidine Alkaloids [Chemical/Ingredient] - Classes

Last uploaded: July 6, 2018

Preferred Name	Pyrrolizidine Alkaloids [Chemical/Ingredient]
Synonyms	Pyrrolizidine Alkaloids
ID	http://purl.bioontology.org/ontology/NDFRT/N0000166982
altLabel	Pyrrolizidine Alkaloids
cui	C0034335
MESH DEFINITION	A group of ALKALOIDS, characterized by a nitrogen-containing necine, occurring mainly in plants of the BORAGINACEAE; COMPOSITAE; and LEGUMINOSAE plant families. They can be activated in the liver by hydrolysis of the ester and desaturation of the necine base to reactive electrophilic pyrrolic CYTOTOXINS.
MESH DUI	D011763
MeSH name	Pyrrolizidine Alkaloids
MESH UI	M0018283
NDFRT kind	INGREDIENT_KIND
notation	N0000166982
NUI	N0000166982
prefLabel	Pyrrolizidine Alkaloids [Chemical/Ingredient]
tui	T109 T131 T123
subClassOf	http://purl.bioontology.org/ontology/NDFRT/N0000007503

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Delete	Mapping To	Ontology	Source
	http://purl.bioontology.org/ontology/MESH/D011763	MESH	CUI
	http://purl.bioontology.org/ontology/MSHFRE/D011763	MSHFRE	CUI