National Drug File - Reference Terminology - Ryanodine [Chemical/Ingredient] - Classes

Last uploaded: July 6, 2018

Preferred Name	Ryanodine [Chemical/Ingredient]
Synonyms	Ryanodol, 3-(1H-pyrrole-2-carboxylate) Ryanodine
ID	http://purl.bioontology.org/ontology/NDFRT/N0000166904
altLabel	Ryanodol, 3-(1H-pyrrole-2-carboxylate) Ryanodine
cui	C0035983
MESH DEFINITION	A methylpyrrole-carboxylate from RYANIA that disrupts the RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL to modify CALCIUM release from SARCOPLASMIC RETICULUM resulting in alteration of MUSCLE CONTRACTION. It was previously used in INSECTICIDES. It is used experimentally in conjunction with THAPSIGARGIN and other inhibitors of CALCIUM ATPASE uptake of calcium into SARCOPLASMIC RETICULUM.
MESH DUI	D012433
MeSH name	Ryanodine
MESH UI	M0019318
NDFRT kind	INGREDIENT_KIND
notation	N0000166904
NUI	N0000166904
prefLabel	Ryanodine [Chemical/Ingredient]
tui	T109 T121
subClassOf	http://purl.bioontology.org/ontology/NDFRT/N0000007503

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Mapping To	Ontology	Source
http://purl.bioontology.org/ontology/CSP/0093-1309	CRISP	CUI
http://purl.bioontology.org/ontology/MSHFRE/D012433	MSHFRE	CUI
http://purl.bioontology.org/ontology/SNMI/C-32013	SNMI	CUI
http://purl.bioontology.org/ontology/SNOMEDCT/40352008	SNOMEDCT	CUI
http://purl.bioontology.org/ontology/SCTSPA/40352008	SCTSPA	CUI
http://purl.bioontology.org/ontology/MESH/D012433	MESH	CUI
http://purl.bioontology.org/ontology/SNMI/C-30331	SNMI	CUI
http://purl.bioontology.org/ontology/CSP/0093-1309	CRISP	CUI