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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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Preferred Name | Glycyrrhizic Acid [Chemical/Ingredient] | |
Synonyms |
Glycyrrhizinic Acid Glycyrrhizin Glycyrrhizic Acid alpha-D-glucopyranosiduronic acid, (3 beta,20 beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl- |
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ID |
http://purl.bioontology.org/ontology/NDFRT/N0000166344 |
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altLabel |
Glycyrrhizinic Acid Glycyrrhizin Glycyrrhizic Acid alpha-D-glucopyranosiduronic acid, (3 beta,20 beta)-20-carboxy-11-oxo-30-norolean-12-en-3-yl 2-O-beta-D-glucopyranuronosyl-
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cui |
C0061751
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MESH DEFINITION |
A widely used anti-inflammatory agent isolated from the licorice root. It is metabolized to GLYCYRRHETINIC ACID, which inhibits 11-BETA-HYDROXYSTEROID DEHYDROGENASES and other enzymes involved in the metabolism of CORTICOSTEROIDS. Therefore, glycyrrhizic acid, which is the main and sweet component of licorice, has been investigated for its ability to cause hypermineralocorticoidism with sodium retention and potassium loss, edema, increased blood pressure, as well as depression of the renin-angiotensin-aldosterone system.
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MESH DUI |
D019695
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MeSH name |
Glycyrrhizic Acid
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MESH UI |
M0029245
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NDFRT kind |
INGREDIENT_KIND
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notation |
N0000166344
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NUI |
N0000166344
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prefLabel |
Glycyrrhizic Acid [Chemical/Ingredient]
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tui |
T109 T121
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subClassOf |
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