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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000011205
http://purl.bioontology.org/ontology/NDFRT/N0000011205
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|---|---|
| Preferred Name | Hirudins [Chemical/Ingredient] |
| Synonyms |
Hirudins
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel | Hirudins
|
|---|---|
| prefLabel | Hirudins [Chemical/Ingredient]
|
| MESH DEFINITION | Single-chain polypeptides of about 65 amino acids (7 kDa) from LEECHES that have a neutral hydrophobic N terminus, an acidic hydrophilic C terminus, and a compact, hydrophobic core region. Recombinant hirudins lack tyr-63 sulfation and are referred to as 'desulfato-hirudins'. They form a stable non-covalent complex with ALPHA-THROMBIN, thereby abolishing its ability to cleave FIBRINOGEN.
|
| MESH DUI | D006629
|
| MESH UI | M0465835
|
| MeSH name | Hirudins
|
| type | |
| tui |
T116
T121
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| notation | N0000011205
|
| Semantic type UMLS property | |
| NUI | N0000011205
|
| cui | C1451270
|
| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |