Preferred Name

Camptothecin [Chemical/Ingredient]

Synonyms

Camptothecin

1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (S)-

ID

http://purl.bioontology.org/ontology/NDFRT/N0000007999

altLabel

Camptothecin

Camptothecine

1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (S)-

cui

C0006812

MESH DEFINITION

An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.

MESH DUI

D002166

MeSH name

Camptothecin

MESH UI

M0003242

NDFRT kind

INGREDIENT_KIND

notation

N0000007999

NUI

N0000007999

prefLabel

Camptothecin [Chemical/Ingredient]

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000007503

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