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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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| Preferred Name | Camptothecin [Chemical/Ingredient] | |
| Synonyms |
Camptothecin Camptothecine 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (S)- |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000007999 |
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| altLabel |
Camptothecin Camptothecine 1H-Pyrano(3',4':6,7)indolizino(1,2-b)quinoline-3,14(4H,12H)-dione, 4-ethyl-4-hydroxy-, (S)-
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| cui |
C0006812
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| MESH DEFINITION |
An alkaloid isolated from the stem wood of the Chinese tree, Camptotheca acuminata. This compound selectively inhibits the nuclear enzyme DNA TOPOISOMERASES, TYPE I. Several semisynthetic analogs of camptothecin have demonstrated antitumor activity.
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| MESH DUI |
D002166
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| MeSH name |
Camptothecin
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| MESH UI |
M0003242
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| NDFRT kind |
INGREDIENT_KIND
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| notation |
N0000007999
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| NUI |
N0000007999
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| prefLabel |
Camptothecin [Chemical/Ingredient]
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| tui |
T109 T121
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| subClassOf |
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