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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000007728
http://purl.bioontology.org/ontology/NDFRT/N0000007728
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|---|---|
| Preferred Name | Quinidine [Chemical/Ingredient] |
| Synonyms |
Quinidine
Chinidin
Cinchonan-9-ol, 6'-methoxy-, (9S)-
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Quinidine
Chinidin
Cinchonan-9-ol, 6'-methoxy-, (9S)-
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|---|---|
| prefLabel | Quinidine [Chemical/Ingredient]
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| MESH DEFINITION | An optical isomer of quinine, extracted from the bark of the CHINCHONA tree and similar plant species. This alkaloid dampens the excitability of cardiac and skeletal muscles by blocking sodium and potassium currents across cellular membranes. It prolongs cellular ACTION POTENTIALS, and decreases automaticity. Quinidine also blocks muscarinic and alpha-adrenergic neurotransmission.
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| MESH DUI | D011802
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| MESH UI | M0018341
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| MeSH name | Quinidine
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| type | |
| tui |
T109
T121
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| Contraindicating class of |
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| notation | N0000007728
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| Semantic type UMLS property | |
| NUI | N0000007728
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| Ingredient of | |
| cui | C0034414
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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