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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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Preferred Name | Busulfan [Chemical/Ingredient] | |
Synonyms |
Busulfan 1,4-Butanediol, dimethanesulfonate Busulphan |
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ID |
http://purl.bioontology.org/ontology/NDFRT/N0000007483 |
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altLabel |
Busulfan 1,4-Butanediol, dimethanesulfonate Busulphan
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cui |
C0006463
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Ingredient of |
http://purl.bioontology.org/ontology/NDFRT/N0000154529 http://purl.bioontology.org/ontology/NDFRT/N0000191839 |
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MESH DEFINITION |
An alkylating agent having a selective immunosuppressive effect on BONE MARROW. It has been used in the palliative treatment of chronic myeloid leukemia (MYELOID LEUKEMIA, CHRONIC), but although symptomatic relief is provided, no permanent remission is brought about. According to the Fourth Annual Report on Carcinogens (NTP 85-002, 1985), busulfan is listed as a known carcinogen.
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MESH DUI |
D002066
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MeSH name |
Busulfan
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MESH UI |
M0003079
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NDFRT kind |
INGREDIENT_KIND
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notation |
N0000007483
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NUI |
N0000007483
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prefLabel |
Busulfan [Chemical/Ingredient]
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tui |
T109 T131 T121
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subClassOf |
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