National Drug File - Reference Terminology

Last uploaded: July 6, 2018
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Preferred Name

Buprenorphine [Chemical/Ingredient]
Synonyms

6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))-

Buprenorphine
ID

http://purl.bioontology.org/ontology/NDFRT/N0000007417
altLabel

6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))-

Buprenorphine
cui

C0006405
Ingredient of

http://purl.bioontology.org/ontology/NDFRT/N0000190963

http://purl.bioontology.org/ontology/NDFRT/N0000188357

http://purl.bioontology.org/ontology/NDFRT/N0000192099

http://purl.bioontology.org/ontology/NDFRT/N0000186545

http://purl.bioontology.org/ontology/NDFRT/N0000182006

http://purl.bioontology.org/ontology/NDFRT/N0000181773

http://purl.bioontology.org/ontology/NDFRT/N0000191154

http://purl.bioontology.org/ontology/NDFRT/N0000192100

http://purl.bioontology.org/ontology/NDFRT/N0000147737

http://purl.bioontology.org/ontology/NDFRT/N0000192256

http://purl.bioontology.org/ontology/NDFRT/N0000022301

http://purl.bioontology.org/ontology/NDFRT/N0000192254

http://purl.bioontology.org/ontology/NDFRT/N0000181772

http://purl.bioontology.org/ontology/NDFRT/N0000189308

http://purl.bioontology.org/ontology/NDFRT/N0000192252

http://purl.bioontology.org/ontology/NDFRT/N0000192250

http://purl.bioontology.org/ontology/NDFRT/N0000192253

http://purl.bioontology.org/ontology/NDFRT/N0000190964

http://purl.bioontology.org/ontology/NDFRT/N0000192255

http://purl.bioontology.org/ontology/NDFRT/N0000164055

http://purl.bioontology.org/ontology/NDFRT/N0000164056

http://purl.bioontology.org/ontology/NDFRT/N0000181771

http://purl.bioontology.org/ontology/NDFRT/N0000191459

http://purl.bioontology.org/ontology/NDFRT/N0000193297

http://purl.bioontology.org/ontology/NDFRT/N0000186544

http://purl.bioontology.org/ontology/NDFRT/N0000192251

http://purl.bioontology.org/ontology/NDFRT/N0000190965

http://purl.bioontology.org/ontology/NDFRT/N0000182005

http://purl.bioontology.org/ontology/NDFRT/N0000192629

http://purl.bioontology.org/ontology/NDFRT/N0000188356
MESH DEFINITION

A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
MESH DUI

D002047
MeSH name

Buprenorphine
MESH UI

M0003054
NDFRT kind

INGREDIENT_KIND
notation

N0000007417
NUI

N0000007417
prefLabel

Buprenorphine [Chemical/Ingredient]
tui

T109

T121
subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000008069
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