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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000007417
http://purl.bioontology.org/ontology/NDFRT/N0000007417
|
|---|---|
| Preferred Name | Buprenorphine [Chemical/Ingredient] |
| Synonyms |
6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))-
Buprenorphine
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel | 6,14-Ethenomorphinan-7-methanol, 17-(cyclopropylmethyl)-alpha-(1,1-dimethylethyl)-4,5-epoxy-18,19-dihydro-3-hydroxy-6-methoxy-alpha-methyl-, (5alpha,7alpha(S))-
Buprenorphine
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|---|---|
| prefLabel | Buprenorphine [Chemical/Ingredient]
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| notation | N0000007417
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| MESH DEFINITION | A derivative of the opioid alkaloid THEBAINE that is a more potent and longer lasting analgesic than MORPHINE. It appears to act as a partial agonist at mu and kappa opioid receptors and as an antagonist at delta receptors. The lack of delta-agonist activity has been suggested to account for the observation that buprenorphine tolerance may not develop with chronic use.
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| MESH UI | M0003054
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| subClassOf | |
| Semantic type UMLS property | |
| MeSH name | Buprenorphine
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| NDFRT kind | INGREDIENT_KIND
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| type | |
| tui |
T109
T121
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| NUI | N0000007417
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| cui | C0006405
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| Ingredient of |
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| MESH DUI | D002047
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| Delete | Subject | Author | Type | Created |
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| No notes to display |