Preferred Name |
Trimetrexate [Chemical/Ingredient] |
|
Synonyms |
Trimetrexate |
|
ID |
http://purl.bioontology.org/ontology/NDFRT/N0000007404 |
|
altLabel |
Trimetrexate 2,4-Quinazolinediamine, 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)- Ipsen Brand of Trimetrexate |
|
cui |
C0085176 |
|
Ingredient of | ||
MESH DEFINITION |
A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect. |
|
MESH DUI |
D016597 |
|
MeSH name |
Trimetrexate |
|
MESH UI |
M0025316 |
|
NDFRT kind |
INGREDIENT_KIND |
|
notation |
N0000007404 |
|
NUI |
N0000007404 |
|
prefLabel |
Trimetrexate [Chemical/Ingredient] |
|
tui |
T109 T121 |
|
subClassOf |
Create mapping