Preferred Name

Trimetrexate [Chemical/Ingredient]

Synonyms

Trimetrexate

ID

http://purl.bioontology.org/ontology/NDFRT/N0000007404

altLabel

Trimetrexate

2,4-Quinazolinediamine, 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)-

Ipsen Brand of Trimetrexate

cui

C0085176

Ingredient of

http://purl.bioontology.org/ontology/NDFRT/N0000148354

MESH DEFINITION

A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.

MESH DUI

D016597

MeSH name

Trimetrexate

MESH UI

M0025316

NDFRT kind

INGREDIENT_KIND

notation

N0000007404

NUI

N0000007404

prefLabel

Trimetrexate [Chemical/Ingredient]

tui

T109

T121

subClassOf

http://purl.bioontology.org/ontology/NDFRT/N0000007605

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