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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000007404
http://purl.bioontology.org/ontology/NDFRT/N0000007404
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|---|---|
| Preferred Name | Trimetrexate [Chemical/Ingredient] |
| Synonyms |
Trimetrexate
2,4-Quinazolinediamine, 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)-
Ipsen Brand of Trimetrexate
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Trimetrexate
2,4-Quinazolinediamine, 5-methyl-6-(((3,4,5-trimethoxyphenyl)amino)methyl)-
Ipsen Brand of Trimetrexate
|
|---|---|
| prefLabel | Trimetrexate [Chemical/Ingredient]
|
| MESH DEFINITION | A nonclassical folic acid inhibitor through its inhibition of the enzyme dihydrofolate reductase. It is being tested for efficacy as an antineoplastic agent and as an antiparasitic agent against PNEUMOCYSTIS PNEUMONIA in AIDS patients. Myelosuppression is its dose-limiting toxic effect.
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| MESH DUI | D016597
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| MESH UI | M0025316
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| MeSH name | Trimetrexate
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| type | |
| tui |
T109
T121
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| notation | N0000007404
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| Semantic type UMLS property | |
| NUI | N0000007404
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| Ingredient of | |
| cui | C0085176
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |