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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000007370
http://purl.bioontology.org/ontology/NDFRT/N0000007370
|
|---|---|
| Preferred Name | Methotrexate [Chemical/Ingredient] |
| Synonyms |
Amethopterin
L-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
Methotrexate
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Amethopterin
L-Glutamic acid, N-(4-(((2,4-diamino-6-pteridinyl)methyl)methylamino)benzoyl)-
Methotrexate
|
|---|---|
| prefLabel | Methotrexate [Chemical/Ingredient]
|
| MESH DEFINITION | An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.
|
| MESH DUI | D008727
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| MESH UI | M0013595
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| MeSH name | Methotrexate
|
| type | |
| tui |
T109
T121
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| Contraindicating class of | |
| notation | N0000007370
|
| Semantic type UMLS property | |
| NUI | N0000007370
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| Ingredient of |
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| cui | C0025677
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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| No notes to display |