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National Drug File - Reference Terminology
| Preferred Name | Tacrolimus [Chemical/Ingredient] | |
| Synonyms |
15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-p Tacrolimus |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000007302 |
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| altLabel |
15,19-Epoxy-3H-pyrido(2,1-c)(1,4)oxaazacyclotricosine-1,7,20,21(4H,23H)-tetrone, 5,6,8,11,12,13,14,15,16,17,18,19,24,25,26,26a-hexadecahydro-5,19-dihydroxy-3-(2-(4-hydroxy-3-methoxycyclohexyl)-1-methylethenyl)-14,16-dimethoxy-4,10,12,18-tetramethyl-8-(2-p Tacrolimus
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| cui |
C0085149
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| Ingredient of |
http://purl.bioontology.org/ontology/NDFRT/N0000160385 http://purl.bioontology.org/ontology/NDFRT/N0000181998 http://purl.bioontology.org/ontology/NDFRT/N0000181999 http://purl.bioontology.org/ontology/NDFRT/N0000160384 http://purl.bioontology.org/ontology/NDFRT/N0000188970 http://purl.bioontology.org/ontology/NDFRT/N0000163039 http://purl.bioontology.org/ontology/NDFRT/N0000188969 http://purl.bioontology.org/ontology/NDFRT/N0000181997 http://purl.bioontology.org/ontology/NDFRT/N0000148372 http://purl.bioontology.org/ontology/NDFRT/N0000161565 http://purl.bioontology.org/ontology/NDFRT/N0000160383 |
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| MESH DEFINITION |
A macrolide isolated from the culture broth of a strain of Streptomyces tsukubaensis that has strong immunosuppressive activity in vivo and prevents the activation of T-lymphocytes in response to antigenic or mitogenic stimulation in vitro.
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| MESH DUI |
D016559
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| MeSH name |
Tacrolimus
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| MESH UI |
M0025261
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| NDFRT kind |
INGREDIENT_KIND
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| notation |
N0000007302
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| NUI |
N0000007302
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| prefLabel |
Tacrolimus [Chemical/Ingredient]
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| tui |
T109 T121
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| subClassOf |
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