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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000007185
http://purl.bioontology.org/ontology/NDFRT/N0000007185
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|---|---|
| Preferred Name | Aprotinin [Chemical/Ingredient] |
| Synonyms |
Bovine Pancreatic Trypsin Inhibitor
Kallikrein-Trypsin Inactivator
Kunitz Pancreatic Trypsin Inhibitor
Trypsin Inhibitor, Basic, Pancreatic
Bovine Kunitz Pancreatic Trypsin Inhibitor
Aprotinin
Trypsin Inhibitor, Kunitz, Pancreatic
Basic Pancreatic Trypsin Inhibitor
BPTI, Basic Pancreatic Trypsin Inhibitor
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Bovine Pancreatic Trypsin Inhibitor
Kallikrein-Trypsin Inactivator
Kunitz Pancreatic Trypsin Inhibitor
Trypsin Inhibitor, Basic, Pancreatic
Bovine Kunitz Pancreatic Trypsin Inhibitor
Aprotinin
Trypsin Inhibitor, Kunitz, Pancreatic
Basic Pancreatic Trypsin Inhibitor
BPTI, Basic Pancreatic Trypsin Inhibitor
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| prefLabel | Aprotinin [Chemical/Ingredient]
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| notation | N0000007185
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| MESH DEFINITION | A single-chain polypeptide derived from bovine tissues consisting of 58 amino-acid residues. It is an inhibitor of proteolytic enzymes including CHYMOTRYPSIN; KALLIKREIN; PLASMIN; and TRYPSIN. It is used in the treatment of HEMORRHAGE associated with raised plasma concentrations of plasmin. It is also used to reduce blood loss and transfusion requirements in patients at high risk of major blood loss during and following open heart surgery with EXTRACORPOREAL CIRCULATION. (Reynolds JEF(Ed): Martindale: The Extra Pharmacopoeia (electronic version). Micromedex, Inc, Englewood, CO, 1995)
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| MESH UI | M0011905
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| subClassOf | |
| Semantic type UMLS property | |
| MeSH name | Aprotinin
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| NDFRT kind | INGREDIENT_KIND
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| type | |
| tui |
T116
T123
T121
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| NUI | N0000007185
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| cui | C0003641
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| Ingredient of | |
| MESH DUI | D007611
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| Delete | Subject | Author | Type | Created |
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