National Drug File - Reference Terminology - Fluorouracil [Chemical/Ingredient] - Classes

Last uploaded: July 6, 2018

Id	http://purl.bioontology.org/ontology/NDFRT/N0000007099 http://purl.bioontology.org/ontology/NDFRT/N0000007099
Preferred Name	Fluorouracil [Chemical/Ingredient]
Synonyms	Fluoruracil 2,4(1H,3H)-Pyrimidinedione, 5-fluoro- 5-FU Fluorouracil 5-Fluorouracil 5FU
Type	http://www.w3.org/2002/07/owl#Class

altLabel	Fluoruracil 2,4(1H,3H)-Pyrimidinedione, 5-fluoro- 5-FU Fluorouracil 5-Fluorouracil 5FU See more See less
prefLabel	Fluorouracil [Chemical/Ingredient]
notation	N0000007099
MESH DEFINITION	A pyrimidine analog that is an antineoplastic antimetabolite. It interferes with DNA synthesis by blocking the THYMIDYLATE SYNTHETASE conversion of deoxyuridylic acid to thymidylic acid.
MESH UI	M0008631
subClassOf	http://purl.bioontology.org/ontology/NDFRT/N0000007953
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T121 http://purl.bioontology.org/ontology/STY/T114
MeSH name	Fluorouracil
NDFRT kind	INGREDIENT_KIND
type	http://www.w3.org/2002/07/owl#Class
tui	T114 T121
NUI	N0000007099
cui	C0016360
Ingredient of	http://purl.bioontology.org/ontology/NDFRT/N0000150430 http://purl.bioontology.org/ontology/NDFRT/N0000146166 http://purl.bioontology.org/ontology/NDFRT/N0000150434 http://purl.bioontology.org/ontology/NDFRT/N0000150431 http://purl.bioontology.org/ontology/NDFRT/N0000150428 http://purl.bioontology.org/ontology/NDFRT/N0000163369 http://purl.bioontology.org/ontology/NDFRT/N0000150433 http://purl.bioontology.org/ontology/NDFRT/N0000192040 http://purl.bioontology.org/ontology/NDFRT/N0000150429 See more See less
MESH DUI	D005472

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