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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000007062
http://purl.bioontology.org/ontology/NDFRT/N0000007062
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|---|---|
| Preferred Name | Cisplatin [Chemical/Ingredient] |
| Synonyms |
Platinum Diamminodichloride
cis-Diamminedichloroplatinum(II)
cis-Dichlorodiammineplatinum(II)
cis-Diamminedichloroplatinum
cis-Platinum
Cisplatin
Platinum, diamminedichloro-, (SP-4-2)-
Dichlorodiammineplatinum
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Platinum Diamminodichloride
cis-Diamminedichloroplatinum(II)
cis-Dichlorodiammineplatinum(II)
cis-Diamminedichloroplatinum
cis-Platinum
Cisplatin
Platinum, diamminedichloro-, (SP-4-2)-
Dichlorodiammineplatinum
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|
|---|---|
| prefLabel | Cisplatin [Chemical/Ingredient]
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| MESH DEFINITION | An inorganic and water-soluble platinum complex. After undergoing hydrolysis, it reacts with DNA to produce both intra and interstrand crosslinks. These crosslinks appear to impair replication and transcription of DNA. The cytotoxicity of cisplatin correlates with cellular arrest in the G2 phase of the cell cycle.
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| MESH DUI | D002945
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| MESH UI | M0004505
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| MeSH name | Cisplatin
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| type | |
| tui |
T197
T121
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| notation | N0000007062
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| Semantic type UMLS property | |
| NUI | N0000007062
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| Ingredient of | |
| cui | C0008838
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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| No notes to display |