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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000007042
http://purl.bioontology.org/ontology/NDFRT/N0000007042
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|---|---|
| Preferred Name | Sulindac [Chemical/Ingredient] |
| Synonyms |
Sulindac
1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Sulindac
1H-Indene-3-acetic acid, 5-fluoro-2-methyl-1-((4-(methylsulfinyl)phenyl)methylene)-, (Z)-
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|---|---|
| prefLabel | Sulindac [Chemical/Ingredient]
|
| notation | N0000007042
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| MESH DEFINITION | A sulfinylindene derivative prodrug whose sulfinyl moiety is converted in vivo to an active NSAID analgesic. Specifically, the prodrug is converted by liver enzymes to a sulfide which is excreted in the bile and then reabsorbed from the intestine. This helps to maintain constant blood levels with reduced gastrointestinal side effects.
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| MESH UI | M0020810
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| Contraindicating class of |
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| subClassOf | |
| Semantic type UMLS property | |
| MeSH name | Sulindac
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| NDFRT kind | INGREDIENT_KIND
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| type | |
| tui |
T109
T121
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| NUI | N0000007042
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| cui | C0038792
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| Ingredient of | |
| MESH DUI | D013467
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| Delete | Subject | Author | Type | Created |
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| No notes to display |