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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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| Preferred Name | Quinine [Chemical/Ingredient] | |
| Synonyms |
Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)- Quinine |
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| ID |
http://purl.bioontology.org/ontology/NDFRT/N0000006907 |
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| altLabel |
Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)- Quinine
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| Contraindicating class of |
http://purl.bioontology.org/ontology/NDFRT/N0000148011 http://purl.bioontology.org/ontology/NDFRT/N0000146933 http://purl.bioontology.org/ontology/NDFRT/N0000178117 |
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| cui |
C0034417
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| Ingredient of | ||
| MESH DEFINITION |
An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
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| MESH DUI |
D011803
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| MeSH name |
Quinine
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| MESH UI |
M0018346
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| NDFRT kind |
INGREDIENT_KIND
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| notation |
N0000006907
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| NUI |
N0000006907
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|
| prefLabel |
Quinine [Chemical/Ingredient]
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| tui |
T109 T121
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| subClassOf |
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