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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000006907
http://purl.bioontology.org/ontology/NDFRT/N0000006907
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|---|---|
| Preferred Name | Quinine [Chemical/Ingredient] |
| Synonyms |
Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)-
Quinine
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Cinchonan-9-ol, 6'-methoxy-, (8alpha,9R)-
Quinine
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|---|---|
| prefLabel | Quinine [Chemical/Ingredient]
|
| notation | N0000006907
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| MESH DEFINITION | An alkaloid derived from the bark of the cinchona tree. It is used as an antimalarial drug, and is the active ingredient in extracts of the cinchona that have been used for that purpose since before 1633. Quinine is also a mild antipyretic and analgesic and has been used in common cold preparations for that purpose. It was used commonly and as a bitter and flavoring agent, and is still useful for the treatment of babesiosis. Quinine is also useful in some muscular disorders, especially nocturnal leg cramps and myotonia congenita, because of its direct effects on muscle membrane and sodium channels. The mechanisms of its antimalarial effects are not well understood.
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| MESH UI | M0018346
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| Contraindicating class of | |
| subClassOf | |
| Semantic type UMLS property | |
| MeSH name | Quinine
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| NDFRT kind | INGREDIENT_KIND
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| type | |
| tui |
T109
T121
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| NUI | N0000006907
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| cui | C0034417
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| Ingredient of | |
| MESH DUI | D011803
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| No notes to display |