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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
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Preferred Name | Cantharidin [Chemical/Ingredient] | |
Synonyms |
4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aalpha,4beta,7beta,7aalpha)- Cantharidin Cantharidine |
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ID |
http://purl.bioontology.org/ontology/NDFRT/N0000006744 |
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altLabel |
4,7-Epoxyisobenzofuran-1,3-dione, hexahydro-3a,7a-dimethyl-, (3aalpha,4beta,7beta,7aalpha)- Cantharidin Cantharidine
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cui |
C0006886
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Ingredient of | ||
MESH DEFINITION |
A toxic compound, isolated from the Spanish fly or blistering beetle (Lytta (Cantharis) vesicatoria) and other insects. It is a potent and specific inhibitor of protein phosphatases 1 (PP1) and 2A (PP2A). This compound can produce severe skin inflammation, and is extremely toxic if ingested orally.
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MESH DUI |
D002193
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MeSH name |
Cantharidin
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MESH UI |
M0003285
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NDFRT kind |
INGREDIENT_KIND
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notation |
N0000006744
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NUI |
N0000006744
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prefLabel |
Cantharidin [Chemical/Ingredient]
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tui |
T109 T131 T121
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subClassOf |
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