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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000006635
http://purl.bioontology.org/ontology/NDFRT/N0000006635
|
|---|---|
| Preferred Name | Cocaine [Chemical/Ingredient] |
| Synonyms |
8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-
Cocaine
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel | 8-Azabicyclo(3.2.1)octane-2-carboxylic acid, 3-(benzoyloxy)-8-methyl-, methyl ester, (1R-(exo,exo))-
Cocaine
|
|---|---|
| prefLabel | Cocaine [Chemical/Ingredient]
|
| MESH DEFINITION | An alkaloid ester extracted from the leaves of plants including coca. It is a local anesthetic and vasoconstrictor and is clinically used for that purpose, particularly in the eye, ear, nose, and throat. It also has powerful central nervous system effects similar to the amphetamines and is a drug of abuse. Cocaine, like amphetamines, acts by multiple mechanisms on brain catecholaminergic neurons; the mechanism of its reinforcing effects is thought to involve inhibition of dopamine uptake.
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| MESH DUI | D003042
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| MESH UI | M0004670
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| MeSH name | Cocaine
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| type | |
| tui |
T109
T131
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| notation | N0000006635
|
| Semantic type UMLS property | |
| NUI | N0000006635
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| Ingredient of | |
| cui | C0009170
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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| No notes to display |