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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000006605
http://purl.bioontology.org/ontology/NDFRT/N0000006605
|
|---|---|
| Preferred Name | Sirolimus [Chemical/Ingredient] |
| Synonyms |
Rapamycin
Sirolimus
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Rapamycin
Sirolimus
|
|---|---|
| prefLabel | Sirolimus [Chemical/Ingredient]
|
| MESH DEFINITION | A macrolide compound obtained from Streptomyces hygroscopicus that acts by selectively blocking the transcriptional activation of cytokines thereby inhibiting cytokine production. It is bioactive only when bound to IMMUNOPHILINS. Sirolimus is a potent immunosuppressant and possesses both antifungal and antineoplastic properties.
|
| MESH DUI | D020123
|
| MESH UI | M0029863
|
| MeSH name | Sirolimus
|
| type | |
| tui |
T109
T195
|
| Contraindicating class of | |
| notation | N0000006605
|
| Semantic type UMLS property | |
| NUI | N0000006605
|
| Ingredient of |
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| cui | C0072980
|
| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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| No notes to display |