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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000006603
http://purl.bioontology.org/ontology/NDFRT/N0000006603
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|---|---|
| Preferred Name | Nitric Oxide [Chemical/Ingredient] |
| Synonyms |
Nitrogen oxide (NO)
Endogenous Nitrate Vasodilator
Nitrogen Monoxide
Nitric Oxide, Endothelium-Derived
Mononitrogen Monoxide
Nitric Oxide
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Nitrogen oxide (NO)
Endogenous Nitrate Vasodilator
Nitrogen Monoxide
Nitric Oxide, Endothelium-Derived
Mononitrogen Monoxide
Nitric Oxide
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| prefLabel | Nitric Oxide [Chemical/Ingredient]
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| MESH DEFINITION | A free radical gas produced endogenously by a variety of mammalian cells, synthesized from ARGININE by NITRIC OXIDE SYNTHASE. Nitric oxide is one of the ENDOTHELIUM-DEPENDENT RELAXING FACTORS released by the vascular endothelium and mediates VASODILATION. It also inhibits platelet aggregation, induces disaggregation of aggregated platelets, and inhibits platelet adhesion to the vascular endothelium. Nitric oxide activates cytosolic GUANYLATE CYCLASE and thus elevates intracellular levels of CYCLIC GMP.
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| MESH DUI | D009569
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| MESH UI | M0014877
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| MeSH name | Nitric Oxide
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| type | |
| tui |
T197
T123
T121
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| notation | N0000006603
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| Semantic type UMLS property | |
| NUI | N0000006603
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| Ingredient of | |
| cui | C0028128
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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