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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000006506
http://purl.bioontology.org/ontology/NDFRT/N0000006506
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|---|---|
| Preferred Name | Caffeine [Chemical/Ingredient] |
| Synonyms |
1,3,7-Trimethylxanthine
Caffeine
1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
1,3,7-Trimethylxanthine
Caffeine
1H-Purine-2,6-dione, 3,7-dihydro-1,3,7-trimethyl-
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|---|---|
| prefLabel | Caffeine [Chemical/Ingredient]
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| MESH DEFINITION | A methylxanthine naturally occurring in some beverages and also used as a pharmacological agent. Caffeine's most notable pharmacological effect is as a central nervous system stimulant, increasing alertness and producing agitation. It also relaxes SMOOTH MUSCLE, stimulates CARDIAC MUSCLE, stimulates DIURESIS, and appears to be useful in the treatment of some types of headache. Several cellular actions of caffeine have been observed, but it is not entirely clear how each contributes to its pharmacological profile. Among the most important are inhibition of cyclic nucleotide PHOSPHODIESTERASES, antagonism of ADENOSINE RECEPTORS, and modulation of intracellular calcium handling.
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| MESH DUI | D002110
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| MESH UI | M0003138
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| MeSH name | Caffeine
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| type | |
| tui |
T109
T121
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| notation | N0000006506
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| Semantic type UMLS property | |
| NUI | N0000006506
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| Ingredient of |
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| cui | C0006644
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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| No notes to display |