National Drug File - Reference Terminology - Mechlorethamine [Chemical/Ingredient] - Classes

Last uploaded: July 6, 2018

Id	http://purl.bioontology.org/ontology/NDFRT/N0000006427 http://purl.bioontology.org/ontology/NDFRT/N0000006427
Preferred Name	Mechlorethamine [Chemical/Ingredient]
Synonyms	Mechlorethamine Chlormethine Chlorethazine Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl- Mustine Nitrogen Mustard Methylchlorethamine Bis(2-chloroethyl)methylamine
Type	http://www.w3.org/2002/07/owl#Class

altLabel	Mechlorethamine Chlormethine Chlorethazine Ethanamine, 2-chloro-N-(2-chloroethyl)-N-methyl- Mustine Nitrogen Mustard Methylchlorethamine Bis(2-chloroethyl)methylamine See more See less
prefLabel	Mechlorethamine [Chemical/Ingredient]
notation	N0000006427
MESH DEFINITION	A biologic alkylating agent that exerts its cytotoxic effects by forming DNA ADDUCTS and DNA interstrand crosslinks, thereby inhibiting rapidly proliferating cells. The hydrochloride is an antineoplastic agent used to treat HODGKIN DISEASE and LYMPHOMA.
MESH UI	M0013168
subClassOf	http://purl.bioontology.org/ontology/NDFRT/N0000007659
Semantic type UMLS property	http://purl.bioontology.org/ontology/STY/T121 http://purl.bioontology.org/ontology/STY/T109 http://purl.bioontology.org/ontology/STY/T131
MeSH name	Mechlorethamine
NDFRT kind	INGREDIENT_KIND
type	http://www.w3.org/2002/07/owl#Class
tui	T109 T131 T121
NUI	N0000006427
cui	C0025033
Ingredient of	http://purl.bioontology.org/ontology/NDFRT/N0000189280 http://purl.bioontology.org/ontology/NDFRT/N0000147897
MESH DUI	D008466

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