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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000006374
http://purl.bioontology.org/ontology/NDFRT/N0000006374
|
|---|---|
| Preferred Name | Ivermectin [Chemical/Ingredient] |
| Synonyms |
Ivermectin
|
| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel | Ivermectin
|
|---|---|
| prefLabel | Ivermectin [Chemical/Ingredient]
|
| MESH DEFINITION | A mixture of mostly avermectin H2B1a (RN 71827-03-7) with some avermectin H2B1b (RN 70209-81-3), which are macrolides from STREPTOMYCES avermitilis. It binds glutamate-gated chloride channel to cause increased permeability and hyperpolarization of nerve and muscle cells. It also interacts with other CHLORIDE CHANNELS. It is a broad spectrum antiparasitic that is active against microfilariae of ONCHOCERCA VOLVULUS but not the adult form.
|
| MESH DUI | D007559
|
| MESH UI | M0011815
|
| MeSH name | Ivermectin
|
| type | |
| tui |
T109
T121
|
| notation | N0000006374
|
| Semantic type UMLS property | |
| NUI | N0000006374
|
| Ingredient of | |
| cui | C0022322
|
| NDFRT kind | INGREDIENT_KIND
|
| subClassOf |
| Delete | Subject | Author | Type | Created |
|---|---|---|---|---|
| No notes to display |