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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000006367
http://purl.bioontology.org/ontology/NDFRT/N0000006367
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|---|---|
| Preferred Name | Thalidomide [Chemical/Ingredient] |
| Synonyms |
Thalidomide
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Thalidomide
1H-Isoindole-1,3(2H)-dione, 2-(2,6-dioxo-3-piperidinyl)-
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|---|---|
| prefLabel | Thalidomide [Chemical/Ingredient]
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| MESH DEFINITION | A piperidinyl isoindole originally introduced as a non-barbiturate hypnotic, but withdrawn from the market due to teratogenic effects. It has been reintroduced and used for a number of immunological and inflammatory disorders. Thalidomide displays immunosuppressive and anti-angiogenic activity. It inhibits release of TUMOR NECROSIS FACTOR-ALPHA from monocytes, and modulates other cytokine action.
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| MESH DUI | D013792
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| MESH UI | M0021267
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| MeSH name | Thalidomide
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| type | |
| tui |
T109
T131
T121
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| notation | N0000006367
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| Semantic type UMLS property | |
| NUI | N0000006367
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| Ingredient of | |
| cui | C0039736
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
| Delete | Subject | Author | Type | Created |
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| No notes to display |