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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000006161
http://purl.bioontology.org/ontology/NDFRT/N0000006161
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|---|---|
| Preferred Name | Dextromethorphan [Chemical/Ingredient] |
| Synonyms |
d-Methorphan
Dextromethorphan
Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
d-Methorphan
Dextromethorphan
Morphinan, 3-methoxy-17-methyl-, (9alpha,13alpha,14alpha)-
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|---|---|
| prefLabel | Dextromethorphan [Chemical/Ingredient]
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| MESH DEFINITION | Methyl analog of DEXTRORPHAN that shows high affinity binding to several regions of the brain, including the medullary cough center. This compound is an NMDA receptor antagonist (RECEPTORS, N-METHYL-D-ASPARTATE) and acts as a non-competitive channel blocker. It is one of the widely used ANTITUSSIVES, and is also used to study the involvement of glutamate receptors in neurotoxicity.
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| MESH DUI | D003915
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| MESH UI | M0006138
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| MeSH name | Dextromethorphan
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| type | |
| tui |
T109
T121
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| notation | N0000006161
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| Semantic type UMLS property | |
| NUI | N0000006161
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| Ingredient of |
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| cui | C0011816
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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