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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000006026
http://purl.bioontology.org/ontology/NDFRT/N0000006026
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|---|---|
| Preferred Name | Rifampin [Chemical/Ingredient] |
| Synonyms |
Rifampicin
Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-
Rifampin
Benemycin
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Rifampicin
Rifamycin, 3-(((4-methyl-1-piperazinyl)imino)methyl)-
Rifampin
Benemycin
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|---|---|
| prefLabel | Rifampin [Chemical/Ingredient]
|
| MESH DEFINITION | A semisynthetic antibiotic produced from Streptomyces mediterranei. It has a broad antibacterial spectrum, including activity against several forms of Mycobacterium. In susceptible organisms it inhibits DNA-dependent RNA polymerase activity by forming a stable complex with the enzyme. It thus suppresses the initiation of RNA synthesis. Rifampin is bactericidal, and acts on both intracellular and extracellular organisms. (From Gilman et al., Goodman and Gilman's The Pharmacological Basis of Therapeutics, 9th ed, p1160)
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| MESH DUI | D012293
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| MESH UI | M0019110
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| MeSH name | Rifampin
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| type | |
| tui |
T109
T195
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| Contraindicating class of |
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| notation | N0000006026
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| Semantic type UMLS property | |
| NUI | N0000006026
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| Ingredient of |
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| cui | C0035608
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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| No notes to display |