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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
Acronym | NDFRT |
Visibility | Public |
Description | National Drug File - Reference Terminology Public Inferred Edition, 2008_03_11 |
Status | Production |
Format | UMLS |
Contact | Michael J. Lincoln MD, michael.lincoln@va.gov |
Categories | Health |
Groups | Unified Medical Language System |
License Information | This ontology is made available via the UMLS. Users of all UMLS ontologies must abide by the terms of the UMLS license. |
Version | Released | Uploaded |
---|---|---|
NDFRT_2018_02_05_18_03_05 (Parsed, Indexed, Metrics, Annotator, Error Diff) | 05/07/2018 | 07/06/2018 |
2017AB (Archived) | 11/06/2017 | 07/06/2018 |
2017AA (Archived) | 05/08/2017 | 04/06/2018 |
2016AB (Archived) | 02/06/2017 | 02/06/2017 |
2016AA (Archived) | 09/06/2016 | 09/06/2016 |
2015AB (Archived) | 07/20/2016 | 07/20/2016 |
2015AA (Archived) | 06/09/2015 | 06/09/2015 |
2014AB (Archived) | 01/29/2015 | 01/29/2015 |
2014AA (Archived) | 05/28/2014 | 05/28/2014 |
2013AB (Archived) | 02/18/2014 | 02/18/2014 |
2013AA (Archived) | 01/14/2014 | 01/14/2014 |
2013AA (Archived) | 05/08/2013 | 09/25/2013 |
2008_03_11 (Archived) | 03/11/2008 | 07/31/2009 |
more... |
- National Drug File – Reference Terminology
- Logically inferred version in OWL of the National Drug File – Reference Terminology (NDF-RT). NDF-RT is the terminology used by FDA and the FedMed collaboration to code these essential pharmacologic properties of medications: Mechanism of Action, Physiologic Effect, Structural Class.
Classes | 36,202 |
Individuals | 0 |
Properties | 53 |
Maximum depth | 11 |
Maximum number of children | 953 |
Average number of children | 3 |
Classes with a single child | 4,051 |
Classes with more than 25 children | 87 |
Classes with no definition | 36,171 |
Jump to:
Id | http://purl.bioontology.org/ontology/NDFRT/N0000006023
http://purl.bioontology.org/ontology/NDFRT/N0000006023
|
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Preferred Name | Phenytoin [Chemical/Ingredient] |
Synonyms |
Diphenylhydantoin
5,5-Diphenylhydantoin
2,4-Imidazolidinedione, 5,5-diphenyl-
Fenitoin
Phenytoin
|
Type | http://www.w3.org/2002/07/owl#Class |
All Properties
altLabel |
Diphenylhydantoin
5,5-Diphenylhydantoin
2,4-Imidazolidinedione, 5,5-diphenyl-
Fenitoin
Phenytoin
|
---|---|
prefLabel | Phenytoin [Chemical/Ingredient]
|
notation | N0000006023
|
MESH DEFINITION | An anticonvulsant that is used to treat a wide variety of seizures. It is also an anti-arrhythmic and a muscle relaxant. The mechanism of therapeutic action is not clear, although several cellular actions have been described including effects on ion channels, active transport, and general membrane stabilization. The mechanism of its muscle relaxant effect appears to involve a reduction in the sensitivity of muscle spindles to stretch. Phenytoin has been proposed for several other therapeutic uses, but its use has been limited by its many adverse effects and interactions with other drugs.
|
MESH UI | M0016580
|
subClassOf | |
Semantic type UMLS property | |
MeSH name | Phenytoin
|
NDFRT kind | INGREDIENT_KIND
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type | |
tui |
T109
T121
|
NUI | N0000006023
|
cui | C0031507
|
Ingredient of |
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|
MESH DUI | D010672
|
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