National Drug File - Reference Terminology

Last uploaded: July 6, 2018
Id http://purl.bioontology.org/ontology/NDFRT/N0000005851
http://purl.bioontology.org/ontology/NDFRT/N0000005851
Preferred Name

Disulfiram [Chemical/Ingredient]
Synonyms
Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2
Tetraethylthiuram Disulfide
Disulfiram
Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl-
Bis(diethylthiocarbamoyl) Disulfide
Type http://www.w3.org/2002/07/owl#Class

All Properties

altLabel
Tetraethylthioperoxydicarbonic Diamide, ((H2N)C(S))2S2
Tetraethylthiuram Disulfide
Disulfiram
Thioperoxydicarbonic diamide (((H2N)C(S))2S2), tetraethyl-
Bis(diethylthiocarbamoyl) Disulfide
prefLabel
Disulfiram [Chemical/Ingredient]
notation
N0000005851
MESH DEFINITION
A carbamate derivative used as an alcohol deterrent. It is a relatively nontoxic substance when administered alone, but markedly alters the intermediary metabolism of alcohol. When alcohol is ingested after administration of disulfiram, blood acetaldehyde concentrations are increased, followed by flushing, systemic vasodilation, respiratory difficulties, nausea, hypotension, and other symptoms (acetaldehyde syndrome). It acts by inhibiting aldehyde dehydrogenase.
MESH UI
M0006600
Contraindicating class of
subClassOf
Semantic type UMLS property
MeSH name
Disulfiram
NDFRT kind
INGREDIENT_KIND
type
tui
T109
T121
NUI
N0000005851
cui
C0012772
Ingredient of
MESH DUI
D004221
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