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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000005763
http://purl.bioontology.org/ontology/NDFRT/N0000005763
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|---|---|
| Preferred Name | Amitriptyline [Chemical/Ingredient] |
| Synonyms |
Amitriptyline
1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Amitriptyline
1-Propanamine, 3-(10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-ylidene)-N,N-dimethyl-
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|---|---|
| prefLabel | Amitriptyline [Chemical/Ingredient]
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| MESH DEFINITION | Tricyclic antidepressant with anticholinergic and sedative properties. It appears to prevent the re-uptake of norepinephrine and serotonin at nerve terminals, thus potentiating the action of these neurotransmitters. Amitriptyline also appears to antagonize cholinergic and alpha-1 adrenergic responses to bioactive amines.
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| MESH DUI | D000639
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| MESH UI | M0000975
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| MeSH name | Amitriptyline
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| type | |
| tui |
T109
T121
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| notation | N0000005763
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| Semantic type UMLS property | |
| NUI | N0000005763
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| Ingredient of |
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| cui | C0002600
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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| No notes to display |