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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000004931
http://purl.bioontology.org/ontology/NDFRT/N0000004931
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|---|---|
| Preferred Name | Insulin [Chemical/Ingredient] |
| Synonyms |
Soluble Insulin
Insulin, Regular
Insulin
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Soluble Insulin
Insulin, Regular
Insulin
|
|---|---|
| prefLabel | Insulin [Chemical/Ingredient]
|
| MESH DEFINITION | A 51-amino acid pancreatic hormone that plays a major role in the regulation of glucose metabolism, directly by suppressing endogenous glucose production (GLYCOGENOLYSIS; GLUCONEOGENESIS) and indirectly by suppressing GLUCAGON secretion and LIPOLYSIS. Native insulin is a globular protein comprised of a zinc-coordinated hexamer. Each insulin monomer containing two chains, A (21 residues) and B (30 residues), linked by two disulfide bonds. Insulin is used as a drug to control insulin-dependent diabetes mellitus (DIABETES MELLITUS, TYPE 1).
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| MESH DUI | D007328
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| MESH UI | M0011417
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| MeSH name | Insulin
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| type | |
| tui |
T125
T116
T121
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| Contraindicating class of | |
| notation | N0000004931
|
| Semantic type UMLS property | |
| NUI | N0000004931
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| Ingredient of |
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| cui | C0021641
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| NDFRT kind | INGREDIENT_KIND
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| subClassOf |
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| No notes to display |