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National Drug File - Reference Terminology
Last uploaded:
July 6, 2018
| Id | http://purl.bioontology.org/ontology/NDFRT/N0000001129
http://purl.bioontology.org/ontology/NDFRT/N0000001129
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|---|---|
| Preferred Name | Epilepsy, Tonic-Clonic [Disease/Finding] |
| Synonyms |
Tonic-Clonic Seizure Syndrome
Epilepsy, Grand Mal
Major Motor Seizure Disorder
Tonic-Clonic Convulsion Disorder
Convulsions, Grand Mal
Tonic-Clonic Seizure Disorder
Tonic Clonic Convulsions
Seizure Disorder, Grand Mal
Tonic-Clonic Convulsion Syndrome
Epilepsy, Tonic-Clonic
Seizure Disorder, Major Motor
Seizure Disorder, Tonic Clonic
Epilepsy, Major
Grand Mal Seizure Disorder
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| Type | http://www.w3.org/2002/07/owl#Class |
All Properties
| altLabel |
Tonic-Clonic Seizure Syndrome
Epilepsy, Grand Mal
Major Motor Seizure Disorder
Tonic-Clonic Convulsion Disorder
Convulsions, Grand Mal
Tonic-Clonic Seizure Disorder
Tonic Clonic Convulsions
Seizure Disorder, Grand Mal
Tonic-Clonic Convulsion Syndrome
Epilepsy, Tonic-Clonic
Seizure Disorder, Major Motor
Seizure Disorder, Tonic Clonic
Epilepsy, Major
Grand Mal Seizure Disorder
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| prefLabel | Epilepsy, Tonic-Clonic [Disease/Finding]
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| MESH DEFINITION | A generalized seizure disorder characterized by recurrent major motor seizures. The initial brief tonic phase is marked by trunk flexion followed by diffuse extension of the trunk and extremities. The clonic phase features rhythmic flexor contractions of the trunk and limbs, pupillary dilation, elevations of blood pressure and pulse, urinary incontinence, and tongue biting. This is followed by a profound state of depressed consciousness (post-ictal state) which gradually improves over minutes to hours. The disorder may be cryptogenic, familial, or symptomatic (caused by an identified disease process). (From Adams et al., Principles of Neurology, 6th ed, p329)
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| MESH DUI | D004830
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| MESH UI | M0007573
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| MeSH name | Epilepsy, Tonic-Clonic
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| type | |
| tui | T047
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| SNOMED CID | 352818000
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| May be treated by |
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| notation | N0000001129
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| Semantic type UMLS property | |
| NUI | N0000001129
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| cui | C0014549
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| NDFRT kind | DISEASE_KIND
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| subClassOf |
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