loading...| Preferred Name |
Dronabinol |
|
| Synonyms |
Delta(9)-Tetrahydrocannibinol Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol Tetrahydrocannabinol Delta-9-THC Abbott 40566 (-)-.DELTA.9-Tetrahydrocannabinol Delta 9-Tetrahydrocannabinol Delta-9-Tetrahydrocannabinol DRONABINOL Delta9-THC Dronabinol Marinol SP 104 SP-104 SYNDROS THC dronabinol |
|
| Definitions |
An isomer of tetrahydrocannabinol (THC) that is the main and most active isomer found in the Cannabis sativa L. plant, with potential anti-emetic, analgesic and appetite stimulating activities. Upon administration, dronabinol, also called delta-9-THC, targets and binds to cannabinoid receptors (CBRs) located in the central nervous system (CNS). Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. In addition, this agent induces analgesia. Urine levels may be used as a marker to determine the exposure to certain preparations containing parts of the cannabis plant, such as marijuana. |
|
| ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C867 |
|
| ALT_DEFINITION |
A synthetic pill form of delta-9-tetrahydrocannabinol (THC), an active ingredient in marijuana that is used to treat nausea and vomiting associated with cancer chemotherapy. |
|
| CAS_Registry |
1972-08-3 |
|
| Chemical_Formula |
C21H30O2 |
|
| code |
C867 |
|
| Concept_In_Subset |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C201600 http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799 |
|
| Contributing_Source |
CTRP FDA HemOnc |
|
| DEFINITION |
An isomer of tetrahydrocannabinol (THC) that is the main and most active isomer found in the Cannabis sativa L. plant, with potential anti-emetic, analgesic and appetite stimulating activities. Upon administration, dronabinol, also called delta-9-THC, targets and binds to cannabinoid receptors (CBRs) located in the central nervous system (CNS). Dronabinol acts directly on the appetite and vomiting control centers in the brain to stimulate appetite and prevent emesis. In addition, this agent induces analgesia. Urine levels may be used as a marker to determine the exposure to certain preparations containing parts of the cannabis plant, such as marijuana. |
|
| Display_Name |
Dronabinol |
|
| FDA_UNII_Code |
7J8897W37S |
|
| FULL_SYN |
Delta(9)-Tetrahydrocannibinol Tetrahydro-6,6,9-trimethyl-3-pentyl-6H-dibenzo(b,d)pyran-1-ol Tetrahydrocannabinol Delta-9-THC Abbott 40566 (-)-.DELTA.9-Tetrahydrocannabinol Delta 9-Tetrahydrocannabinol Delta-9-Tetrahydrocannabinol DRONABINOL Delta9-THC Dronabinol Marinol SP 104 SP-104 SYNDROS THC dronabinol |
|
| label |
Dronabinol |
|
| Legacy Concept Name |
Dronabinol |
|
| NCI_Drug_Dictionary_ID |
39707 |
|
| NSC Number |
134454 |
|
| PDQ_Closed_Trial_Search_ID |
39707 |
|
| PDQ_Open_Trial_Search_ID |
39707 |
|
| Preferred_Name |
Dronabinol |
|
| prefixIRI |
Thesaurus:C867 |
|
| Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
| UMLS_CUI |
C0039663 |
|
| subClassOf |