National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Selenium

Synonyms

SELENIUM

Se

Selenium

selenium

Definitions

A nonmetallic chemical element found in trace amounts in human body. Selenium primarily occurs in vivo as selenocompounds, mostly selenoproteins such as glutathione peroxidase and thioredoxin reductase (enzymes responsible for detoxification). Alone or in combination with Vitamin E, selenocompounds act as antioxidants. These agents scavenge free radicals; prevent blood clots by inhibiting platelet aggregation; strengthen the immune system; and have been shown, in some instances, to inhibit chromosomal damage and mutations. Exhibiting chemopreventive activity, selenocompounds also inhibit the induction of protein kinase C.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C825

Accepted_Therapeutic_Use_For

Dandruff; Psoriasis; Seborrheic dermatitis; Tinea capitis; Tinea versicolor

ALT_DEFINITION

A mineral that is needed by the body to stay healthy. It is being studied in the prevention and treatment of some types of cancer. Selenium is a type of antioxidant.

CAS_Registry

7782-49-2

CHEBI_ID

CHEBI:27568

CHEBI:36904

Chemical_Formula

Se

code

C825

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C176424

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116978

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C142799

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C116977

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

CTRP

FDA

DEFINITION

A nonmetallic chemical element found in trace amounts in human body. Selenium primarily occurs in vivo as selenocompounds, mostly selenoproteins such as glutathione peroxidase and thioredoxin reductase (enzymes responsible for detoxification). Alone or in combination with Vitamin E, selenocompounds act as antioxidants. These agents scavenge free radicals; prevent blood clots by inhibiting platelet aggregation; strengthen the immune system; and have been shown, in some instances, to inhibit chromosomal damage and mutations. Exhibiting chemopreventive activity, selenocompounds also inhibit the induction of protein kinase C.

Display_Name

Selenium

FDA_UNII_Code

H6241UJ22B

FULL_SYN

SELENIUM

Se

Selenium

selenium

label

Selenium

Legacy Concept Name

Selenium

NCI_Drug_Dictionary_ID

38725

PDQ_Closed_Trial_Search_ID

38725

PDQ_Open_Trial_Search_ID

38725

Preferred_Name

Selenium

prefixIRI

Thesaurus:C825

Semantic_Type

Pharmacologic Substance

Element, Ion, or Isotope

UMLS_CUI

C0036581

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1940

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Delete Mapping To Ontology Source
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D012643 RH-MESH LOOM
http://localhost/plosthes.2017-1#4558 PLOSTHES LOOM
http://doe-generated-ontology.com/OntoAD#C0036581 ONTOAD LOOM
http://purl.bioontology.org/ontology/LNC/LP14283-3 LOINC LOOM
http://purl.bioontology.org/ontology/phenX/050900 PHENX LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148196 NDFRT LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015366 PMAPP-PMO LOOM
http://www.semanticweb.org/admin/ontologies/2022/7/MIO:01434 MIO LOOM
http://purl.obolibrary.org/obo/MESH_D012643 BERO LOOM
http://scai.fraunhofer.de/CSEO#Selenium CSEO LOOM
http://purl.bioontology.org/ontology/PDQ/CDR0000038725 PDQ LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/22038003 SNOMEDCT LOOM
http://www.co-ode.org/ontologies/galen#Selenium GALEN LOOM
http://purl.bioontology.org/ontology/CPT/84255 CPT LOOM
http://bmi.utah.edu/ontologies/hfontology/C0036581 HFO LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.578.700 RH-MESH LOOM
http://purl.bioontology.org/ontology/CSP/1852-9448 CRISP LOOM
http://purl.jp/bio/4/id/200906051759610970 IOBC LOOM
http://purl.bioontology.org/ontology/LNC/MTHU007657 LOINC LOOM
https://go.drugbank.com/drugs/DB11135 MDM LOOM
http://purl.bioontology.org/ontology/MESH/D012643 MESH LOOM
http://purl.bioontology.org/ontology/NDDF/000864 NDDF LOOM
http://purl.bioontology.org/ontology/npo#NPO_948 NPO LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#11166 OCHV LOOM
http://sweetontology.net/matrMineral/Selenium SWEET LOOM
http://www.projecthalo.com/aura#Selenium AURA LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D01.268.185.850 RH-MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/9641 RXNORM LOOM
http://purl.bioontology.org/ontology/VANDF/4020392 VANDF LOOM
http://purl.obolibrary.org/obo/NCIT_C825 BERO LOOM
http://www.pepathway.org/peo/1.2#Selenium PE-O LOOM
http://id.nlm.nih.gov/mesh/D012643 MDM LOOM
http://www.cea.fr/ontotoxnuc#Selenium ONTOTOXNUC LOOM
http://purl.bioontology.org/ontology/RCD/X7987 RCD LOOM
http://www.co-ode.org/ontologies/ont.owl#Selenium DILON LOOM
http://www.semanticweb.org/ontologies/2018/1/ProstateCancer.owl#Selenium PCAO LOOM
http://radlex.org/RID/RID11828 RADLEX LOOM
http://purl.bioontology.org/ontology/MEDLINEPLUS/C0036581 MEDLINEPLUS LOOM
http://purl.bioontology.org/ontology/MEDDRA/10039918 MEDDRA LOOM
http://purl.obolibrary.org/obo/CHEBI_27568 CHEAR LOOM
http://purl.obolibrary.org/obo/CHEBI_27568 HHEAR LOOM
http://purl.obolibrary.org/obo/OMIT_0013540 OMIT LOOM