Preferred Name |
Dextromethorphan |
|
Synonyms |
DEXTROMETHORPHAN Dextromethorphan DXM |
|
Definitions |
A synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. |
|
ID |
http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62022 |
|
CAS_Registry |
125-71-3 |
|
CHEBI_ID |
CHEBI:4470 |
|
Chemical_Formula |
C18H25NO |
|
code |
C62022 |
|
Concept_In_Subset | ||
Contributing_Source |
FDA |
|
DEFINITION |
A synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex. |
|
FDA_UNII_Code |
7355X3ROTS |
|
FULL_SYN |
DEXTROMETHORPHAN Dextromethorphan DXM |
|
Has_Salt_Form | ||
label |
Dextromethorphan |
|
Legacy Concept Name |
Dextromethorphan_Base |
|
Preferred_Name |
Dextromethorphan |
|
prefixIRI |
Thesaurus:C62022 |
|
Semantic_Type |
Organic Chemical Pharmacologic Substance |
|
UMLS_CUI |
C0011816 |
|
subClassOf |