National Cancer Institute Thesaurus

Last uploaded: November 25, 2019
Preferred Name

Dextromethorphan

Synonyms

DXM

Dextromethorphan

DEXTROMETHORPHAN

Definitions

A synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C62022

CAS_Registry

125-71-3

CHEBI_ID

CHEBI:4470

Chemical_Formula

C18H25NO

code

C62022

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A synthetic, methylated dextrorotary analogue of levorphanol, a substance related to codeine and a non-opioid derivate of morphine. Dextromethorphan exhibits antitussive activity and is devoid of analgesic or addictive property. This agent crosses the blood-brain-barrier and activates sigma opioid receptors on the cough center in the central nervous system, thereby suppressing the cough reflex.

FDA_UNII_Code

7355X3ROTS

FULL_SYN

DXM

Dextromethorphan

DEXTROMETHORPHAN

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C423

label

Dextromethorphan

Legacy_Concept_Name

Dextromethorphan_Base

Preferred_Name

Dextromethorphan

prefixIRI

ncit:C62022

Semantic_Type

Pharmacologic Substance

Organic Chemical

UMLS_CUI

C0011816

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C2199

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http://purl.bioontology.org/ontology/LNC/LA28643-7 LOINC LOOM
http://purl.obolibrary.org/obo/dinto_DB00514 DINTO LOOM
http://purl.bioontology.org/ontology/SNMI/C-88130 SNMI LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.132.577.249.200 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387114001 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/NDDF/004427 NDDF LOOM
http://purl.bioontology.org/ontology/UATC/R05DA09 ATC LOOM
http://www.drugbank.ca/drugs/DB00514 FTC LOOM
http://purl.obolibrary.org/obo/CHEBI_4470 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_4470 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_4470 GO-PLUS LOOM
http://purl.obolibrary.org/obo/CHEBI_4470 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4470 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_4470 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_4470 DIDEO LOOM
http://purl.obolibrary.org/obo/CHEBI_4470 HINO LOOM
http://purl.obolibrary.org/obo/CHEBI_4470 NIFSTD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D003915 RH-MESH LOOM
http://purl.bioontology.org/ontology/LNC/MTHU004183 LOINC LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.497.212 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.615.723.795.200 RH-MESH LOOM
http://stirdf.jst.go.jp/id/200907070908698485 IOBC LOOM
http://purl.bioontology.org/ontology/MESH/D003915 MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0011816 OCHV LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.549.686.212 RH-MESH LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005735 FASTO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005735 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005735 DMTO LOOM
http://purl.bioontology.org/ontology/LNC/LP16105-6 LOINC LOOM
http://www.co-ode.org/ontologies/galen#Dextromethorphan GALEN LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#3830 OCHV LOOM
http://purl.bioontology.org/ontology/VANDF/4018052 VANDF LOOM
http://purl.bioontology.org/ontology/RXNORM/3289 RXNORM LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005740 DDO LOOM
http://purl.obolibrary.org/obo/DDO.owl#DDO_0005740 DMTO LOOM
http://purl.bioontology.org/ontology/CSP/4007-0038 CRISP LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000146393 NDFRT LOOM
http://purl.jp/bio/4/id/200906042174065480 IOBC LOOM