National Cancer Institute Thesaurus

Last uploaded: November 25, 2019
Preferred Name

Sparfloxacin

Synonyms

Sparfloxacin

SPARFLOXACIN

5-amino-1-cyclopropyl-7-[(3R,5S)3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-quinoline-3-carboxylic acid

Zagam

Definitions

A fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription. Sparfloxacin was withdrawn from the U.S. market due to a high incidence of phototoxicity.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61950

CAS_Registry

110871-86-8

CHEBI_ID

CHEBI:9212

Chemical_Formula

C19H22F2N4O3

code

C61950

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A fluoroquinolone antibiotic that inhibits bacterial DNA gyrase, thereby inhibiting DNA replication and transcription. Sparfloxacin was withdrawn from the U.S. market due to a high incidence of phototoxicity.

FDA_UNII_Code

Q90AGA787L

FULL_SYN

Sparfloxacin

SPARFLOXACIN

5-amino-1-cyclopropyl-7-[(3R,5S)3,5-dimethylpiperazin-1-yl]-6,8-difluoro-4-oxo-quinoline-3-carboxylic acid

Zagam

label

Sparfloxacin

Legacy_Concept_Name

Sparfloxacin

Preferred_Name

Sparfloxacin

prefixIRI

ncit:C61950

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0052585

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C280

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C795

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http://purl.obolibrary.org/obo/DRON_00011571 DRON LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000148455 NDFRT LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#13532 OCHV LOOM
http://purl.obolibrary.org/obo/ARO_3000666 ARO LOOM
http://purl.obolibrary.org/obo/CHEBI_9212 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_9212 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_9212 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_9212 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9212 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_9212 GENEPIO LOOM
http://purl.obolibrary.org/obo/CHEBI_9212 NIFSTD LOOM
http://stirdf.jst.go.jp/id/200907068469035399 IOBC LOOM
http://purl.bioontology.org/ontology/UATC/J01MA09 ATC LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0052585 OCHV LOOM
http://purl.obolibrary.org/obo/dinto_DB01208 DINTO LOOM
http://www.drugbank.ca/drugs/DB01208 FTC LOOM
http://purl.jp/bio/4/id/200906026566258639 IOBC LOOM
http://purl.bioontology.org/ontology/VANDF/4020985 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#C061363 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-557C0 SNMI LOOM
http://purl.bioontology.org/ontology/LNC/MTHU009179 LOINC LOOM
http://purl.bioontology.org/ontology/LNC/LP17280-6 LOINC LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/387554008 SNOMEDCT LOOM
http://purl.bioontology.org/ontology/MESH/C061363 MESH LOOM
http://purl.bioontology.org/ontology/RXNORM/18469 RXNORM LOOM