National Cancer Institute Thesaurus

Last uploaded: February 23, 2024
Preferred Name

Methicillin

Synonyms

METHICILLIN

Methicillin

Definitions

A semisynthetic, narrow spectrum beta-lactamase-resistant penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Methicillin binds to specific penicillin-binding proteins (BPBs) on the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial lysis.

ID

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C61842

CAS_Registry

61-32-5

CHEBI_ID

CHEBI:6827

Chemical_Formula

C17H20N2O6S

code

C61842

Concept_In_Subset

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C63923

Contributing_Source

FDA

DEFINITION

A semisynthetic, narrow spectrum beta-lactamase-resistant penicillin antibiotic with bactericidal and beta-lactamase resistant activity. Methicillin binds to specific penicillin-binding proteins (BPBs) on the bacterial cell wall, thereby preventing the cross-linkage of peptidoglycans, which are critical components of the bacterial cell wall. This leads to an interruption of the bacterial cell wall and causes bacterial lysis.

FDA_UNII_Code

Q91FH1328A

FULL_SYN

METHICILLIN

Methicillin

Has_Salt_Form

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C47611

label

Methicillin

Legacy Concept Name

Methicillin

Preferred_Name

Methicillin

prefixIRI

Thesaurus:C61842

Semantic_Type

Pharmacologic Substance

UMLS_CUI

C0025643

subClassOf

http://ncicb.nci.nih.gov/xml/owl/EVS/Thesaurus.owl#C1500

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http://purl.obolibrary.org/obo/MESH_D008712 BERO LOOM
http://purl.bioontology.org/ontology/MESH/D008712 MESH LOOM
http://stirdf.jst.go.jp/id/200907061377101390 IOBC LOOM
http://www.phoc.org.cn/pmo/class/PMO_00015917 PMAPP-PMO LOOM
http://purl.bioontology.org/ontology/RCD/x01I7 RCD LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.438.260.825.500 RH-MESH LOOM
http://purl.bioontology.org/ontology/SNMI/C-54440 SNMI LOOM
http://purl.bioontology.org/ontology/VANDF/4019826 VANDF LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D008712 RH-MESH LOOM
http://purl.bioontology.org/ontology/NDFRT/N0000022613 NDFRT LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D04.075.080.875.099.221.750.500 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#C0025643 OCHV LOOM
http://purl.bioontology.org/ontology/LNC/LP15975-3 LOINC LOOM
http://purl.bioontology.org/ontology/RXNORM/2181306 RXNORM LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.886.108.750.500 RH-MESH LOOM
http://purl.obolibrary.org/obo/CHEBI_6827 PDRO LOOM
http://purl.obolibrary.org/obo/CHEBI_6827 DINTO LOOM
http://purl.obolibrary.org/obo/CHEBI_6827 COVID-19 LOOM
http://purl.obolibrary.org/obo/CHEBI_6827 BERO LOOM
http://purl.obolibrary.org/obo/CHEBI_6827 BIOMODELS LOOM
http://purl.obolibrary.org/obo/CHEBI_6827 DRON LOOM
http://purl.obolibrary.org/obo/CHEBI_6827 CHEBI LOOM
http://purl.obolibrary.org/obo/CHEBI_6827 NIFSTD LOOM
http://purl.obolibrary.org/obo/CHEBI_6827 PHIPO LOOM
http://purl.obolibrary.org/obo/CHEBI_6827 GENEPIO LOOM
http://purl.bioontology.org/ontology/NDDF/004833 NDDF LOOM
http://purl.bioontology.org/ontology/SNOMEDCT/373515001 SNOMEDCT LOOM
http://www.gamuts.net/entity#methicillin GAMUTS LOOM
http://purl.jp/bio/4/id/200906057801224618 IOBC LOOM
http://purl.obolibrary.org/obo/OMIT_0009771 OMIT LOOM
http://purl.bioontology.org/ontology/LNC/MTHU008454 LOINC LOOM
http://purl.obolibrary.org/obo/NCIT_C61842 BERO LOOM
http://purl.bioontology.org/ontology/CSP/0199-7894 CRISP LOOM
http://www.co-ode.org/ontologies/galen#Methicillin GALEN LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D02.065.589.099.750.500 RH-MESH LOOM
http://phenomebrowser.net/ontologies/mesh/mesh.owl#D03.605.084.737.500 RH-MESH LOOM
http://sbmi.uth.tmc.edu/ontology/ochv#8036 OCHV LOOM
http://purl.obolibrary.org/obo/ARO_0000015 ARO LOOM